Code of federal regulations title 21 food and drugs the code of federal regulations cfr is a codification of the general and permanent rules published in the federal register by the executive. This information is current as of april 1 2020 this online reference for cfr title 21 is updated once a year for the most up to date version of cfr title 21 go to the electronic code of federal regulations ecfr this database includes a codification of the general and permanent rules published in the federal register by the executive departments and agencies of the federal government. Title 21 of the cfr is reserved for rules of the food and drug administration each title or volume of the cfr is revised once each calendar year a revised title 21 is issued on approximately . Code of federal regulations title 21 volume 5 revised as of april 1 2020 cite 21cfr314110 title 21 food and drugs chapter i food and drug administration department of health and human services subchapter d drugs for human use part 314 applications for fda approval to market a new drug subpart d fda action on applications and abbreviated applications sec 314110 . Cfr code of federal regulations title 21 the information on this page is current as of april 1 2020 for the most up to date version of cfr title 21 go to the electronic code of federal